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Peripheral neuropathy is nerve damage caused by several different conditions. Health conditions that can cause peripheral neuropathy include:. The best way to prevent peripheral neuropathy is to manage medical conditions that put you at risk.
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This content does not have an English version. This content does not have an Arabic version. Overview Peripheral neuropathy happens when the nerves that are located outside of the brain and spinal cord peripheral nerves are damaged.
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By Mayo Clinic Staff. Show references Peripheral neuropathy. National Institute of Neurological Disorders and Stroke. Accessed March 12, What is peripheral neuropathy?
The Foundation for Peripheral Neuropathy. Rutkove SB. Overview of polyneuropathy. Feldman EL, et al. Treatment of diabetic neuropathy. Ami T. Allscripts EPSi. Mayo Clinic. March 13, Causes of peripheral neuropathy.
Neurological examinations. Goldman L, et al. Peripheral neuropathies. In: Goldman-Cecil Medicine. Elsevier; Peripheral neuropathy treatments. Peripheral neuropathy adult. Mayo Clinic; Rakel D, et al.
Peripheral neuropathy. In: Integrative Medicine. Karri J, et al. The use of Scrambler therapy in treating chronic pain syndromes: A systematic review. Related Anti-seizure medications Hypothyroidism: Can it cause peripheral neuropathy?
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: Diabetic neuropathy complications| Diabetes and Nerve Damage | CDC | Diabetuc your feet every day with RMR and heart rate variability water neuropath mild soap. We are not sure exactly Sports nutrition for performance this is, but could be to do Diabetic neuropathy complications cooler temperatures in Diabeic evening, stress at the end of a long day and fewer distractions in the evening meaning you notice the pain more. Side effects can include dry mouth, sleepiness, dizziness, and constipation. Media Requests. Show the heart some love! If you have CAN, you'll probably need to have regular check-ups so your heart function can be monitored. |
| Diabetic Neuropathy: Treatment, Symptoms, Causes | Therapeutic ultrasound is another type of physical therapy that uses very high-frequency sound waves to stimulate the tissue beneath the skin. This can help some people to regain sensitivity in their feet. Diabetic neuropathy can contribute to a number of high-risk complications, ranging from heart rate changes to visual disturbances. This can lead to an inability to feel cuts or sores, and infection might occur as a result. Untreated infection in a limb can result in the need for amputation. Smoking also increases the risk of foot problems in people with certain types of diabetic neuropathy. A podiatrist can help with foot care, and a healthcare provider can give advice on quitting smoking. Each affects a different set of nerves and has a different range of effects. Autonomic neuropathy harms automatic processes in the body, such as digestion. Peripheral neuropathy damages nerves in the toes, fingers, hands, and feet. Diagnosis includes a range of scans, and tests for ankle reflexes, sensation, and skin texture and tone. Treatment involves several types of physical therapy and medication to control pain and nerve conduction. As people with diabetic neuropathy tend not to feel injuries on the feet, regular inspection of the feet is necessary to avoid undetected infection and the possible loss of limbs. The best way to minimize diabetic neuropathy is by maintaining good blood sugar control and regular foot care. If you take Metformin for a long time, which is a commonly used medication in the treatment of type 2 diabetes, consider having a Vitamin B12 level checked as well, as Metformin can lower the B12 level which can also cause neuropathy. Maria Prelipcean, MD Answers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice. Peripheral neuropathy involves damage to the peripheral nerves. This can cause various sensations, including pain. Here, learn more about the symptoms…. What are the benefits of a foot massage for diabetic neuropathy? Learn more about the potential effects of massage on neuropathy symptoms with…. What symptoms might a person with diabetic neuropathy experience? Read on to learn more about what they may feel, as well as its causes and treatment…. Find out how long diabetic neuropathy takes to develop. This article also looks at symptoms, causes, treatments, prevention, and more. What is diabetic autonomic neuropathy? Read on to learn more about this potential complication of diabetes, including how it occurs, symptoms, and…. My podcast changed me Can 'biological race' explain disparities in health? Why Parkinson's research is zooming in on the gut Tools General Health Drugs A-Z Health Hubs Health Tools Find a Doctor BMI Calculators and Charts Blood Pressure Chart: Ranges and Guide Breast Cancer: Self-Examination Guide Sleep Calculator Quizzes RA Myths vs Facts Type 2 Diabetes: Managing Blood Sugar Ankylosing Spondylitis Pain: Fact or Fiction Connect About Medical News Today Who We Are Our Editorial Process Content Integrity Conscious Language Newsletters Sign Up Follow Us. Medical News Today. Health Conditions Health Products Discover Tools Connect. What to know about diabetic neuropathy. Medically reviewed by Maria Prelipcean, M. Types Symptoms Images Diagnosis Treatment Complications Takeaway. How we vet brands and products Medical News Today only shows you brands and products that we stand behind. Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we: Evaluate ingredients and composition: Do they have the potential to cause harm? Fact-check all health claims: Do they align with the current body of scientific evidence? Assess the brand: Does it operate with integrity and adhere to industry best practices? We do the research so you can find trusted products for your health and wellness. Read more about our vetting process. Was this helpful? Share on Pinterest Peripheral neuropathy can lead to a loss of sensation in the feet. Share on Pinterest A physician will carry out a foot exam and may check blood pressure. Q: I have type 2 diabetes. How do I prevent diabetic neuropathy? A: The best way to minimize diabetic neuropathy is by maintaining good blood sugar control and regular foot care. How we reviewed this article: Sources. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. We avoid using tertiary references. We link primary sources — including studies, scientific references, and statistics — within each article and also list them in the resources section at the bottom of our articles. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Share this article. Latest news Ovarian tissue freezing may help delay, and even prevent menopause. RSV vaccine errors in babies, pregnant people: Should you be worried? Nerve damage can cause health problems ranging from mild numbness to pain that makes it hard to do normal activities. Half of all people with diabetes have nerve damage. The good news is that you can help prevent or delay it by keeping your blood sugar as close to your target levels as possible. There are four main types of nerve damage. You can have more than one type. Symptoms depend on the type of nerve damage you have and which nerves are affected. Your feet may be very sensitive to touch—even a bed sheet can hurt. These are all symptoms of peripheral nerve damage. It generally starts in the feet, usually in both feet at once. Sometimes amputation removal by surgery is necessary. Finding and treating foot problems early can lower your chances of developing a serious infection. Learn how to care for your feet , including how to check them yourself and what kind of shoes to wear. Nerve damage can cause muscles in your digestive tract to slow down or stop working. Learn more about how diabetes can affect your digestion. Autonomic nerve damage affects your heart, bladder, stomach, intestines, sex organs, or eyes. Symptoms may include:. Proximal nerve damage affects nerves in the thighs, hips, buttocks, or legs. It can also affect the stomach and chest area. Focal nerve damage affects single nerves, most often in your hand, head, torso, or leg. Keeping your blood sugar as close to your target range as possible is the best way to help prevent or delay nerve damage. Other things you can do are:. Most people with diabetes can prevent serious nerve damage complications. Stay on schedule with all of your self-checks, exams, and appointments with a diabetes care schedule. Skip directly to site content Skip directly to page options Skip directly to A-Z link. Español Other Languages. Diabetes and Nerve Damage. Español Spanish. Minus Related Pages. |
| StatPearls [Internet]. | From Mayo Clinic to your inbox. Dabetic things you Diabetic neuropathy complications do are:. Exercise for arthritis relief your complicatkons clean Diabetic neuropathy complications dry. Autonomic Peripheral Neuropathy. There are different types of diabetic neuropathy that affect different areas of your body, causing a variety of symptoms. Proximal neuropathy diabetic polyradiculopathy This type of neuropathy often affects nerves in the thighs, hips, buttocks or legs. |
Diabetic neuropathy complications -
If the nerves that control the bladder are damaged, the bladder may not empty completely when urinating. Bacteria can build up in the bladder and kidneys, causing urinary tract infections.
Nerve damage can also affect the ability to feel the need to urinate or to control the muscles that release urine, leading to leakage incontinence. Sharp drops in blood pressure. Damage to the nerves that control blood flow can affect the body's ability to adjust blood pressure.
This can cause a sharp drop in pressure when standing after sitting or lying down, which may lead to lightheadedness and fainting. Digestive problems. If nerve damage occurs in the digestive tract, constipation or diarrhea, or both are possible.
Diabetes-related nerve damage can lead to gastroparesis, a condition in which the stomach empties too slowly or not at all. This can cause bloating and indigestion.
Sexual dysfunction. Autonomic neuropathy often damages the nerves that affect the sex organs. Men may experience erectile dysfunction. Women may have difficulty with lubrication and arousal. Increased or decreased sweating. Nerve damage can disrupt how the sweat glands work and make it difficult for the body to control its temperature properly.
Blood sugar management The American Diabetes Association ADA recommends that people living with diabetes have a glycated hemoglobin A1C test at least twice a year. Foot care Foot problems, including sores that don't heal, ulcers and even amputation, are common complications of diabetic neuropathy.
To protect the health of your feet: Check your feet every day. Look for blisters, cuts, bruises, cracked and peeling skin, redness, and swelling. Use a mirror or ask a friend or family member to help examine parts of your feet that are hard to see.
Keep your feet clean and dry. Wash your feet every day with lukewarm water and mild soap. Don't soak your feet. Dry your feet and between your toes thoroughly. Moisturize your feet. This helps prevent cracking.
But don't get lotion between your toes because it might encourage fungal growth. Trim your toenails carefully. Cut your toenails straight across. File the edges carefully so that you have smooth edges.
If you can't do this yourself, a specialist in foot problems podiatrist can help. Wear clean, dry socks. Look for socks made of cotton or moisture-wicking fibers that don't have tight bands or thick seams. Wear cushioned shoes that fit well.
Wear closed-toed shoes or slippers to protect your feet. Make sure your shoes fit properly and allow your toes to move.
A foot specialist can teach you how to buy properly fitted shoes and to prevent problems such as corns and calluses.
If you qualify for Medicare, your plan may cover the cost of at least one pair of shoes each year. By Mayo Clinic Staff. Apr 29, Show References. Ferri FF. Diabetic polyneuropathy. In: Ferri's Clinical Advisor Elsevier; Accessed Dec.
Diabetic neuropathy. National Institute of Diabetes and Digestive and Kidney Diseases. Accessed Jan. American Diabetes Association. Standards of medical care in diabetes — Diabetes Care. Accessed Nov. Peripheral neuropathy adult. Mayo Clinic; Feldman EL, et al.
Management of diabetic neuropathy. Diabetes and foot problems. Jankovic J, et al. Disorders of peripheral nerves. In: Bradley and Daroff's Neurology in Clinical Practice. Diabetic neuropathy can contribute to a number of high-risk complications, ranging from heart rate changes to visual disturbances.
This can lead to an inability to feel cuts or sores, and infection might occur as a result. Untreated infection in a limb can result in the need for amputation. Smoking also increases the risk of foot problems in people with certain types of diabetic neuropathy.
A podiatrist can help with foot care, and a healthcare provider can give advice on quitting smoking. Each affects a different set of nerves and has a different range of effects. Autonomic neuropathy harms automatic processes in the body, such as digestion.
Peripheral neuropathy damages nerves in the toes, fingers, hands, and feet. Diagnosis includes a range of scans, and tests for ankle reflexes, sensation, and skin texture and tone. Treatment involves several types of physical therapy and medication to control pain and nerve conduction.
As people with diabetic neuropathy tend not to feel injuries on the feet, regular inspection of the feet is necessary to avoid undetected infection and the possible loss of limbs. The best way to minimize diabetic neuropathy is by maintaining good blood sugar control and regular foot care.
If you take Metformin for a long time, which is a commonly used medication in the treatment of type 2 diabetes, consider having a Vitamin B12 level checked as well, as Metformin can lower the B12 level which can also cause neuropathy. Maria Prelipcean, MD Answers represent the opinions of our medical experts.
All content is strictly informational and should not be considered medical advice. Peripheral neuropathy involves damage to the peripheral nerves.
This can cause various sensations, including pain. Here, learn more about the symptoms…. What are the benefits of a foot massage for diabetic neuropathy? Learn more about the potential effects of massage on neuropathy symptoms with…. What symptoms might a person with diabetic neuropathy experience?
Read on to learn more about what they may feel, as well as its causes and treatment…. Find out how long diabetic neuropathy takes to develop. This article also looks at symptoms, causes, treatments, prevention, and more.
What is diabetic autonomic neuropathy? Read on to learn more about this potential complication of diabetes, including how it occurs, symptoms, and…. My podcast changed me Can 'biological race' explain disparities in health? Why Parkinson's research is zooming in on the gut Tools General Health Drugs A-Z Health Hubs Health Tools Find a Doctor BMI Calculators and Charts Blood Pressure Chart: Ranges and Guide Breast Cancer: Self-Examination Guide Sleep Calculator Quizzes RA Myths vs Facts Type 2 Diabetes: Managing Blood Sugar Ankylosing Spondylitis Pain: Fact or Fiction Connect About Medical News Today Who We Are Our Editorial Process Content Integrity Conscious Language Newsletters Sign Up Follow Us.
Medical News Today. Health Conditions Health Products Discover Tools Connect. What to know about diabetic neuropathy. Medically reviewed by Maria Prelipcean, M. Types Symptoms Images Diagnosis Treatment Complications Takeaway. How we vet brands and products Medical News Today only shows you brands and products that we stand behind.
Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we: Evaluate ingredients and composition: Do they have the potential to cause harm?
Fact-check all health claims: Do they align with the current body of scientific evidence? There are several medications that are useful for the treatment of diabetic neuropathy and have been approved by the US Food and Drug Administration FDA , including duloxetine and pregabalin.
Other medications are also useful, including tricyclic medications eg, amitriptyline , gabapentin, tramadol, and alpha-lipoic acid [ 5 ].
Tricyclic antidepressants — There are several tricyclic antidepressants available for the treatment of chronic pain, including amitriptyline, nortriptyline, and desipramine.
Clinical trials have shown that tricyclic antidepressant drugs are effective for patients with painful diabetic neuropathy. The dose of tricyclic antidepressants used to treat diabetic neuropathy is typically much lower than that used to treat depression.
These medications are usually taken at bedtime, starting with a low dose and gradually increasing over a period of several weeks. People with heart disease should not take amitriptyline or nortriptyline.
Tricyclic medications can be taken with gabapentin and pregabalin but should not be taken with duloxetine. Side effects can include dry mouth, sleepiness, dizziness, and constipation. Duloxetine — Duloxetine is an antidepressant that is often effective in relieving pain caused by diabetic neuropathy.
In short-term clinical trials, duloxetine was more effective than placebo. However, the long-term effectiveness and safety of duloxetine for diabetic neuropathy is uncertain [ 6 ]. There are no trials comparing duloxetine with other drugs for the treatment of diabetic polyneuropathy.
Duloxetine is usually taken by mouth once per day on a full stomach, although in some cases it is taken twice per day. It should not be taken by people who take other antidepressant medications see 'Tricyclic antidepressants' above.
Side effects can include nausea, sleepiness, dizziness, decreased appetite, and constipation. Gabapentin — Gabapentin is an anti-seizure medication. It is usually taken by mouth three times per day. Side effects can include dizziness and confusion.
Gabapentin can be taken with a tricyclic antidepressant or duloxetine. In some cases, gabapentin can be taken at night to prevent pain during sleep.
Pregabalin — Pregabalin is an anti-seizure medication, similar to gabapentin. Pregabalin is taken by mouth, starting at bedtime at a low dose and then gradually increasing to three times per day over a period of several weeks. Side effects can include dizziness, sleepiness, confusion, swelling in the feet and ankles, and weight gain.
It may be possible to become addicted to pregabalin, and changes in dosing should be monitored carefully. Pregabalin can be taken with duloxetine or tricyclic antidepressants but not with gabapentin. Anesthetic drugs — Lidocaine is an anesthetic drug that may be recommended if other treatments have not improved pain.
It is applied to the painful area in a patch, which slowly releases the medication over time. Patches should stay in place for no more than 12 hours in any hour period.
Alpha-lipoic acid — Alpha-lipoic acid ALA is an antioxidant medication. Several short-term trials showed that it was helpful in relieving pain caused by diabetic neuropathy. Thus, ALA may be recommended to people with diabetic neuropathy who do not improve with or who cannot tolerate other treatments.
However, longer-term studies are still needed to confirm its safety and effectiveness. In the United States, ALA is available without a prescription as a dietary supplement. It is usually taken by mouth once per day. Your healthcare provider is the best source of information for questions and concerns related to your medical problem.
This article will be updated as needed on our web site www. Related topics for patients, as well as selected articles written for healthcare professionals, are also available. Some of the most relevant are listed below. Patient level information — UpToDate offers two types of patient education materials.
The Basics — The Basics patient education pieces answer the four or five key questions a patient might have about a given condition.
These articles are best for patients who want a general overview and who prefer short, easy-to-read materials. Patient education: Type 2 diabetes The Basics Patient education: Nerve damage caused by diabetes The Basics Patient education: The ABCs of diabetes The Basics Patient education: Neuropathic pain The Basics Patient education: Diabetes and infections The Basics.
Beyond the Basics — Beyond the Basics patient education pieces are longer, more sophisticated, and more detailed. These articles are best for patients who want in-depth information and are comfortable with some medical jargon.
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